Searchable abstracts of presentations at key conferences in endocrinology

ea0056oc8.4 | MicroRNAs as biomarkers in endocrine diseases | ECE2018

Detecting blood micro-RNAs and proteins associated with Graves’ disease and orbitopathy

Biscarini Filippo , Zhang Lei , Masetti Giulia , Covelli Danila , Colucci Giuseppe , Eckstein Anja , Kaiser U , Draman Shazli , Muller Ilaria , Lucini Luigi , Ludgate Marian , Salvi Mario

Graves’ Disease (GD) affects about 2% of the population in the UK, with female predominance. A proportion of GD patients (5–50%) develop orbitopathy (GO), which is characterized by tissue remodeling in the orbit leading to protrusion of the eye (proptosis). Blood biomarkers associated with GD or GO could be useful diagnostic or prognostic tools for researchers and clinicians. Within the framework of INDIGO IAPP-612116 (Investigation of Novel biomarkers and Definition...